Priming principle does not produce faster or better intubating conditions than a single bolus injection. Rocuronium 1.0 mg/kg may be a suitable alternative for succinylcholine 1.0 mg/kg during rapid-sequence intubation. The intubating conditions of groups I and II were better than those of groups III and IV (P < 0.0083). Group II had intubating conditions similar to group I. ![]() the cessation of spontaneous ventilation involves considerable risk if the provider does not intubate or ventilate the patient in a timely manner. ![]() TOF counts of group I were lower than those of groups III and IV, and those of group II were lower than group III (P < 0.0083). Rapid sequence intubation (RSI) is an airway management technique that produces inducing immediate unresponsiveness (induction agent) and muscular relaxation (neuromuscular blocking agent) and is the fastest and most effective means of controlling the emergency airway. Intubation was performed 60 seconds after the administration of muscle relaxant and intubating conditions were evaluated by clinical scoring (Table 1), and train-of-four (TOF) count of the adductor pollicis by accelerography. Group I (n = 12) received succinylcholine 1.0 mg/kg, group II (n = 15) received rocuronium 1.0 mg/kg, group III (n = 16) received rocuronium 0.6 mg/kg as a single bolus dose, and group IV (n = 16) received a priming dose of rocuronium 0.06 mg/kg followed three minutes later by rocuronium 0.54 mg/kg. METHODSįifty nine ASA physical status 1 and 2 adult patients scheduled for elective surgeries were anesthetized with thiopental sodium 5 mg/kg and muscle relaxant using a rapid-sequence technique. The purpose of this study was to compare tracheal intubating conditions by following different rocuronium doses and application techniques versus succinylcholine. Rocuronium has been reported to develop a rapid onset of action and may be suitable as a component of a rapid-sequence intubation. ![]() Succinylcholine is still the most frequently used muscle relaxant for rapid-sequence intubation despite its well-known side effects. Jung Won Park, Chong Wha BaekÄepartment of Anesthesiology and Pain Medicine, College of Medicine, Chung Ang University, Seoul, Korea. DOI: Rapid-Sequence Intubation with Rocuronium. Clinical Research Article Korean J Anesthesiol.
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